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None had proof of retinal, electric motor or growth problems during 12 months of follow-up.

Irreparable retinal harm has been noted in some clients that had obtained high-dosage or lasting 4-aminoquinoline treatment for discoid and also wide spread lupus erythematosus, or rheumatoid joint inflammation.

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Retinopathy seems dose associated as well as has occurred within a number of months (hardly ever) to several years of daily therapy.